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Description
About Celgene
Celgene Corporation is committed to delivering innovative therapies designed to improve the lives of patients worldwide. We are a global biopharmaceutical company with operations in more than 60 countries that is helping to turn incurable cancers into chronic, manageable conditions. We are seeking talented professionals as we continue to grow and advance our efforts in oncology and hematology. If you’d like to join a company where you can make a difference, please consider the Celgene family.
Prerequisites
Ph.D. with 3-5 years of experience or M.S. with 5 to 7 years of experience
Summary
Qualifications:
• At least 3 years of experience in biotechnology or pharmaceutical industry; pre-clinical, non-
clinical, or exploratory development experience preferred
• Prior knowledge and experience analyzing high dimensional large data sets resulting from
gene expression, genotyping, especially clustering and classification methods and
predictive modeling and simulation is essential
• Requires significant knowledge of statistical theory for application to the design and analysis
of experiments, must have worked in a team environment, where interactions with research
scientists led to improved study/experimental design
• Requires thorough operational understanding of linear statistical models, multivariate
analysis, statistical association tests, bootstrap methods, multiple comparison correction
methods for hypothesis testing and principal component analysis (PCA)
• Knowledge of regulatory agency requirements for genomic data submission and experience
designing clinical trials for the prospective validation of biomarkers is highly desirable
• Oncology therapy area experience is essential, including working knowledge of the
biochemical and signaling pathways, public data sources, CaBIG, and familiarity with clinical
endpoints and standard biomarker metrics
• Familiarity with current, leading edge genomics platforms is also required
• Self motivated with the ability to work independently, set priorities, and impact multiple
simultaneous projects
• Ability to work in a fast-paced multifunctional team environment, interact with a wide variety of
customers and provide guidance to non-statisticians, high level of comfort with exploratory
analysis and the fluid, fast-paced nature of an industrial research organization
• Demonstrated programming capability in SAS or R, and facility with Spotfire is essential;
ability to aggregate and process data in PERL/PYTHON or other scripting environment, and
knowledge of SQL considered a “plus”
• Strong publication track record in high impact peer reviewed journals
Description:
• Working with bioinformaticians, provide statistical support, including computational biology
and programming, for both discovery biology and translational development projects
• Responsible for selection and implementation of appropriate statistical methods for design
and data analysis for clinical-stage and non-clinical projects
• Perform statistical analysis of complex data sets through the use of large relational
databases
• Develop, optimize and improve data analysis and mining protocols including accessing and
incorporating information-rich public databases
• Be key point-of-contact and knowledge resource for scientists in discovery research and
translational development, bioinformaticians, and biostatisticians in the clinical development
organization
• Promote data visualization and communication technologies, specifically web-based tools, to
effectively interact across multiple sites
• Write non-regulatory statistical analysis reports and contribute to clinical study reports
• For translational development projects, interact with the clinical biostatistics group and
contribute to Statistical Analysis Plans
• Responsible for continual process improvements to meet business needs
• Some travel to other Celgene corporate sites may be required
• Position can be based in San Diego or San Francisco, CA
Equal Employment Opportunity
Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.
Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.
Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should Celgene support of a potential employee’s temporary visa application be construed to guarantee success of that application or amend or otherwise invalidate the at-will employment relationship between the employee and Celgene.
Details:
Job Id:
10389
Posted / Updated:
11/6/2009 10:50:22 PM
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