Scientist - Protein Technologies

Amgen's Therapeutic Discovery organization is seeking a collaborative Scientist to join the Protein Technologies group at our South San Francisco site. Protein Technologies is responsible for designing, planning and executing on the generation of key enabling reagents to support early discovery of small and large molecule therapeutics and ground-breaking modalities.

The Scientist will be a part of a multidisciplinary team with capabilities in molecular engineering, cloning, expression and purification of proteins, including antibodies, bispecifics and membrane proteins. The ideal candidate will have broad laboratory training, deep scientific curiosity and a positive approach to working in a team-based research environment along with a track record of creative problem-solving and enthusiasm for taking on difficult research challenges.

In our mission to serve patients, speed is absolutely critical. We're rapidly expanding our hiring initiatives and are excited to unite with the most passionate and forward thinking scientific minds who want to join our team - working toward our mission of advancing high potential programs for cancer patients around the world.

Key Responsibilities include:
  • Work cross functionally with our therapeutic areas to design, produce and characterize key protein reagents aimed at enabling both small molecule and large molecule discovery projects
  • Act as a technical leader to bring innovative approaches to difficult purifications including multi-subunit protein complexes
  • Provide scientific results that support the generation of publications and patents; participate in internal and external scientific meetings

Basic Qualifications

Doctorate degree


Master's degree and 4 years of scientific experience


Bachelor's degree and 6 years of scientific experience

Preferred Qualifications
  • Ph.D. in biochemistry, protein engineering or related discipline with additional 1+ year(s) of relevant experience
  • Detailed knowledge in recombinant expression, protein biochemistry (including affinity, ion exchange, HIC, SEC chromatography) and method development
  • Familiarity with chromatography hardware and software (GE AKTA, Agilent HPLC)
  • Proven microbiology skills culturing E. coli and yeast
  • Experience with insect cell culture
  • Biochemistry analytical experience (SDS PAGE, Western Blot, HPLC, Mass Spectrometry)
  • Strong written/verbal communication and interpersonal skills
  • Desire to be a team player in a dynamic, cross-functional environment
  • Demonstrated scientific analysis and problem-solving skills as evidenced by a strong publication record.

Our culture is what makes Amgen a special place to work. We have a powerful shared purpose around our mission - to serve patients. We respect one another, recognize contributions, and have embedded collaboration, trust, empowerment and inclusion in all that we do.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.