Principal Scientist, Late Stage Oncology, Translational Bioinformatics

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients’ lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

This scientist is responsible for applying cutting-edge bioinformatics, statistics, and data analysis methods; working with clinical and large-scale omics data and biomarker data sets that include WES, RNA-Seq, DNA-Seq, IHC, flow cytometry, and soluble cytokines from BMS’s industrial-leading late stage oncology clinical studies; influencing development strategies and advancing BMS late stage oncology pipeline. This scientist also have the exciting opportunity to make major contributions to scientific knowledge of cancer disease biology, and to directly impact treatment of cancer patients.

Responsibilities
  • Engage late stage clinical development teams, biomarker scientists, biostatisticians, and others key stakeholders to define and execute biomarker data analysis plan for late stage oncology clinical studies
  • Perform analysis of clinical and biomarker datasets (e.g., large-scale omics datasets including RNASeq, Exome and Whole Genome Sequencing, single cell sequencing) and derive clinically meaningful interpretations
  • Identify potential biomarkers for patient enrichment strategies and gain mechanistic insights of responses and resistances to oncology treatments
  • Summarize analysis results and report conclusions to BMS decision-making bodies; help communicating conclusions to regulatory agencies and the broad scientific communities


Qualifications
  • Ph.D. in bioinformatics, engineering, statistics, cancer biology, immunology, genetics, or similar natural science fields with 4+ years of industry experiences or equivalent
  • Broad experience with data generated by one or more high-throughput molecular assays: next-generation sequencing, flow cytometry, mass spectrometry proteomics, etc.
  • Strong experience in the use of a high-level programming language such as R, MATLAB, Python or Perl for complex data analysis and reproducible research practices
  • Experiences working with clinical study data is required; familiar with late stage clinical development process is a strong plus
  • Deep understanding of disease biology in oncology is a strong plus
  • Ability to work both independently and collaboratively, and to handle several concurrent, fast-paced projects while conforming with rigorous requirements of clinical studies
  • Strong problem-solving and collaboration skills, and rigorous and creative thinking
  • Excellent communication, data presentation, and visualization skills
  • Capable of establishing strong working relationships across the organization


Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

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