Director, Health Evidence & Outcomes Research, Pipeline & BD, Oncology & Vaccines

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The Health Economics & Outcomes Research (HEOR) Director, will serve as a principal HEOR strategist for early development oncology and vaccines. In collaboration with the asset development team, the Senior Director will formulate HEOR strategy and conduct/oversee evidence generation activities, in particular, real world data (RWD) studies, to support the asset in the early pipeline phase and prepare for phase 3. The Director is responsible for the overall quality, scientific and technical excellence of HEOR deliverables.

The execution of this position will require the ability to develop economic models for cost-effectiveness and budget impact, particularly for broad population-based patient targets (i.e. vaccines) in addition to integrate / recommend patient-reported outcomes data in clinical trial protocols in addition to close collaboration with Clinical, Commercial, PHI Oncology & Vaccines Business Unit Strategists, and Medical.

This position will function with a 'One Patient & Health Impact' mindset and will work in a closely aligned fashion with the Oncology PHI team members to ensure there is a single and coordinated view on strategy and delivery. This position reports to the Patient & Health Impact Early Clinical & Business Development Oncology & Vaccines Integrated Team Lead.

  • Independently lead HEOR strategy development and implementation to support patient-centric and payer-optimized development scenarios including prioritization of high value programs.
  • Develops evidence generation activities, such as: RWD studies of comparative effectiveness and cost; design and implementation of clinical trials with HEOR components; and early economic models, aligned with the overall product strategy.
  • Lead development of early economic modeling for population selection and early pricing.
  • Able to influence and shape the clinical development plan utilizing individual depth of knowledge and experience in value evidence generation and reimbursement.
  • Represent Pfizer's interests in high level interactions with influential bodies (affiliates, international health administration bodies, advocacy groups, specialty associations, etc.).
  • Provide relevant input into selection of patient population and comparators within clinical trials to enable demonstration of robust incremental clinical value over standard of care that can facilitate optimal patient access.
  • Develop and propose the selection, related analyses, interpretation and communication of Patient Reported Outcomes (PRO) measures as appropriate for assigned clinical trials, registries, and prospective real world studies.
  • Collaborate with local affiliates to identify the best study design in preparation of Phase 3.
  • Lead appropriate data dissemination plans and communicate in a timely manner evidence generated to various stakeholders via publications and conference presentations.


Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

  • PhD in relevant discipline (health services research, epidemiology, health economics, psychology, etc.) with 7+ years of work experience in the conduct of outcomes research to evaluate health care interventions.
  • Or a Master's degree in a relevant discipline with 8+ years.
  • Or a Bachelor's degree in a relevant discipline with 10+ years of experience - with pharmaceutical research in several therapeutic areas evaluating health care interventions with 5+ years of that research experience conducting health economics, health related quality of life and epidemiology studies in the pharmaceutical industry.
  • Has substantial technical knowledge and extensive experience of planning and delivering HEOR programs, particularly RWD studies and cost-effectiveness modeling, across multiple therapeutic areas, with significant experience in the oncology area. Has wide professional networks and established reputation within external OR community.
  • Has wide experience and knowledge of the external OR/Clinical/Regulatory/ Reimbursement environment and has made substantial and innovative contributions to the development and direction of the Outcomes Research discipline.
  • Demonstrated track record of progressive contribution through scientific publications, posters, presentations in clinical and/or health services journals/conferences.
  • Knowledge and experience in the oncology therapeutic area is preferred.
  • Past experience with early development, clinical trials, patient reported outcomes and real world study design and implementation is desirable.
  • Demonstrated ability to manage multiple projects involving complex processes, significant budget, competing deadlines and rapidly shifting priorities.
  • Excellent interpersonal skills required; ability to understand and respond to multiple internal and external customers and influence in a matrix environment.
  • Excellent oral and written English communication skills required.
  • Strong project management abilities (contracting, budgeting, vendor management) essential.
  • Skilled in functioning within a matrix organization where managing through influence is required.

  • Ability to travel internationally

Other Job Details:
  • Eligible for Employee Referral Bonus: YES


Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

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