Senior Scientist, Vaccine Process Research & Development

Job Description

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology we collaborate to discover the next medical breakthrough.

The Vaccine Process Development (VPD) department in West Point, PA is seeking a highly motivated scientist/engineer to join their downstream process development team in support of our Company's expanding vaccine pipeline. The VPD downstream group develops purification processes for the manufacture of vaccine candidates encompassing a diverse range of biomolecules, including viruses, recombinant protein subunits, nucleic acids, and polysaccharide-protein conjugates.

In this role, you will be responsible for applying sound scientific understanding and engineering principles to help develop, optimize, scale-up, and transfer of downstream processes for clinical and commercial manufacture. You will work in an inter-disciplinary environment as an individual scientific contributor under the supervision of a senior scientist. The successful candidate will have a background in biological science or bio/chemical engineering and strong expertise in hands-on, laboratory work. Experience in protein and virus purification using techniques, such as ultrafiltration, chromatography, dead-end filtration and centrifugation, is required. Experience in engineering, characterization, and purification of vaccine/ protein targets, including but not limited to (1) elucidating protein structure, (2) engineering new protein targets, (3) developing biophysical and biochemical assays in solving fundamental protein interaction problems is a plus. To support technology transfers, experience in cGMP practices is also desired. We look for candidates who are self-motivated, independent, well-organized, have problem-solving skills and can think strategically. We look for team players and candidates who demonstrate the ability to communicate results of his/her work in both verbal and written formats.

Education Minimum Requirement:

BS in Chemical Engineering or Biological Sciences or related discipline with a minimum of 7 years' experience or

MS in Chemical Engineering or Biological Sciences or related discipline with a minimum of 4 years' experience or

PhD degree in Biological Sciences or Bio/Chemical Engineering with 3+ years of hands-on, laboratory work in the field of bioprocess purification development or 1 year of industrial experience

Required Experience and Skills:
  • Proficiency in downstream purification technologies (e.g. ultrafiltration, chromatography, precipitation, centrifugation)
  • Background in vaccine or biologics process development (downstream)
  • Well-developed organizational, record-keeping, and problem-solving skills, with an attention to detail

Preferred Experience and Skills:
  • Strong laboratory skill set designing and executing experiments independently in a manner that meets quality and timeline expectations.
  • Hands-on work with protein and polysaccharide, nucleic acid, or viral purification, bioconjugation, and HPLC methods.
  • Understanding of cGMP principles and experience in cGMP manufacturing
  • Experience in engineering, characterization, and purification of vaccine/ protein targets.
  • Strong written and verbal communication skills required to interact with key stakeholders, customers, and external vendors
  • Ability to work independently and/or in a team environment and is results oriented
  • Experience with Biosafety Level 2 operations and technology transfer.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science" and that great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are ...

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for ...

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.

Invent. Impact. Inspire.


In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:


VISA Sponsorship:

Travel Requirements:
No Travel Required

Flexible Work Arrangements:
Work Week

1st - Day

Valid Driving License:

Hazardous Material(s):

Number of Openings:

Requisition ID:R123663