Senior Scientist, Bio Process

Job Description

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology we collaborate to discover the next medical breakthrough.

The Biologics Process Research & Development organization within our company's Research Laboratories is responsible for developing the drug substance manufacturing processes for our company's biologics pipeline, including cell line, upstream and downstream process development. We work closely with colleagues in Discovery, Pre-clinical and Early Development to rapidly develop manufacturing processes for diverse biotherapeutics, and efficiently manufacture material to supply clinical trials. We are also responsible for late stage/commercial process development and development of new manufacturing technologies. We work with our partners in our company's Manufacturing Division to commercialize and launch new products

We are seeking a highly motivated scientist to join the Biologics Upstream Pilot Plant Technologies Group within Biologics PR&D, as part of the team charged with supporting the operations of the mammalian and microbial bench top bioreactors and introducing innovative technologies. Candidate is expected to work in a team atmosphere in close collaboration with BioProcess development scientists, facility engineering, lab automation and safety groups.

  • Introduction and evaluation of novel technologies and process analytical tools
  • Champion the set up and operations of microbial fermenters
  • Lead the expansion and troubleshooting of mammalian perfusions
  • Work closely with the lab automation team for process automation and control to streamline benchtop bioreactor operations
  • Support pipeline programs for first-in-human and commercial processes, efficiently developing high yield, robust, and scalable cell culture processes.
  • Scale-up and technology transfer of bioprocesses to manufacturing facilities
  • Data analysis, data interpretation, manuscript preparation, publication and presentations
  • Contribute to a safe and compliant laboratory work environment

  • BS in Chemical/Biochemical Engineering or related discipline with 7 years of relevant experience; or Master's degree with 4 years of relevant experience; or Ph.D. with relevant academic or industrial experience.

Required Experience and Skills:
  • Microbial fermentation lab or pilot scale experience
  • Solid scientific understanding and hands-on experience in cell culture and bench scale bioreactor operations
  • Demonstrated ability for independent execution of experiments
  • Excellent interpersonal skills; ability to work in a matrixed team environment and collaborate with both internal and external partners including vendors

Preferred Experience and Skills:
  • Basic understanding of statistical methods and computer programming/analysis packages like SIMCA, JMP
  • Understanding of bioreactor control systems and automation; PAT tools like Raman and biocapacitance
  • Basic understanding of high throughput systems like ambr15, ambr250 bioreactors
  • Demonstrated ability to think critically with excellent problem solving and troubleshooting skills

Our employees are the key to our company's success. We demonstrate our commitment to our employees by offering a competitive and valuable rewards program. Our company's benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people that matter the most in their lives.

Our company is an equal opportunity employer, M/F/D/V - proudly embracing diversity in all of its manifestations. Former Military, Transitioning Service Members, National Guard & Reserves - We value your past and present service

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science" that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are ...

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for ...

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.

Invent. Impact. Inspire.


In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

For more information about personal rights under Equal Employment Opportunity, visit:

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

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Requisition ID:R124845