Scientist I - Computational Biology and Data Analyst

Job Description

About This Role

Our group focuses on identifying conserved pathways and genes between preclinical models ( in-vivo and in-vitro ) and human, as well as identifying novel targets based on human molecular data leveraging NGS. You will be responsible for integrating multi-omics data and establishing computational frameworks. Additionally, you will develop deep learning models to infer the gene expression occurring in humans that cannot be directly measured, based on observations from model systems.

What You Will Do
  • Investigate conserved pathways and genes between models ( in-vivo and in-vitro ) and human, utilizing RNA-seq and single-cell RNA-seq data.
  • Identify novel therapeutic targets for neurodegenerative diseases by integrative analysis of human molecular data – Genetics, Epigenetics, transcriptomics, and proteomics data.
  • Develop a framework to infer gene expression dynamics in human disease progression based on measurements in model systems, using deep neural network.
  • Support programs with internal and external ‘omics data.

Who You Are

You enjoy developing deep learning models to infer the gene expression occurring in humans that cannot be directly measured, based on observations from model systems. You have developed deep neural network architecture and latent space interpolation, as well as expertise in RNA-seq and single-cell RNA-seq data analysis.

Qualifications

Required Skills
  • PhD in bioinformatics, computational biology, systems biology, computer science, or in related fields, or an MS with equivalent research experience (6 years+)
  • Bulk- and single-cell/nucleus RNA-seq data analysis
  • Deep learning and latent space interpolation, using GAN and/or AE.
  • Creative use of systems biology methods for developing necessary computational frameworks
  • Proficient in R, Python, and use of HPC clusters, in the context of computational biology

Preferred Skills
  • Deliver and present the results to project teams that help establish therapeutic target strategy
  • Demonstrated ability to work independently by designing, executing, and troubleshooting given tasks
  • Excellent verbal, written communication, and presentation skills

*LI-RD8



Additional Information

Biogen’s US Alzheimer’s Franchise is looking to recruit proven and ambitious sales achievers with at least five years of experience in pharma, specialty, hospital, med device/capital equipment, and/or biotech sales.
In this field-based, specialty sales representative position you will be called upon to sell our products with key stakeholders in the Alzheimer’s Disease community: including Neurologists and allied health professionals.

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