Senior Scientist

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients’ lives through science.In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

We are currently seeking a Senior Scientist to join Bristol Myers Squibb Biologics Development group in Summit, New Jersey. The Senior Scientist in Global Upstream Bio-Process Development will be working in a dynamic team setting across cell line, upstream/downstream process development, and analytical groups to

develop highly efficient and robust upstream processes to support BMS’s biologics pipeline. The candidate will be responsible for leading/supporting upstream development projects for upstream process development, main

activities include clone selection, platform fit and process optimization, process characterization, scale-up and tech transfer for clinical manufacturing. The candidate will be responsible for supporting IND/IMPD filings with authoring high quality technical reports. The candidate will also contribute to continued platform improvement and technology development efforts to further the upstream development workflow.

Responsibilities will include, but are not limited to, the following:
  • Using a systematic approach to improve upstream process platform, and to ensure scale-up and technology transfer to clinical manufacturing.
  • Participating in the development of in-house platform media for multiple cell lines to reach high productivity
  • Collaborating closely with the cell line development group on clone selection and platform adaptation or improvement
  • Investigating cellular metabolism and process parameters on the product quality, and to develop a strategy for IP protection
  • Providing prompt technical support for solving real-time manufacturing issues as well as necessary SME assessment for deviation investigation
  • Staying current with industry standards, trends, new technical developments, and all applicable regulations and guidances
  • Writing technical summary and development reports for efficient knowledge management and regulatory filing support
  • Publishing or presenting scientific findings in peer-reviewed journals or conferences, and contributing to industrial collaborations

Qualifications:

Required
  • Ph.D. in chemical engineering, biochemistry, bioengineering, cell biology or related fields with 2-4 years or MS with > 8 years of industry experience.
  • Hands-on experience with mammalian or microbial cell culture in a laboratory environment
  • Strong skills in critical thinking, laboratory experimentation, and data analysis
  • Candidates should possess good oral and written communication skills, excellent interpersonal skills, and have demonstrated the ability to work in a team environment
  • Excellent verbal and written communication skills with a proven record on publications and presentation in scientific forums
  • Excellent organizational and time management skills

Preferred
  • Excellent scientific understanding of biology and engineering principles for cell culture processes and recombinant protein production
  • Experience with cell culture media and process optimization based on mechanistic understanding of cell biology and metabolism.
  • Experience with applying omics, metabolic flux analysis, and/or cell-based assays to understand cell physiology and metabolism related to cell culture performance and product quality modulation
  • Solid knowledge and hands-on experience with statistical and computational tools (e.g. Design of Experiments, multivariate data analysis, etc.).
  • Experience with perfusion bioreactor system and/or continuous bioprocessing
  • Solid track record of scientific contributions with ability to deliver high quality presentations/publications/patents


Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or any part of the recruitment process direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

R1545380-en-us