Scientist I/II, Biologics Drug Discovery

Job Description

About This Role

We are seeking a Scientist to join Biogen’s Tissue-Enhanced Delivery Technologies unit within the Biologics Drug Discovery (BDD) team, contributing to our mission to design, optimize, and develop therapeutics to improve the lives of patients with neurodegenerative disease.

What You’ll Do
  • Establish and perform in vivo pharmacokinetic and pharmacodynamic studies for therapeutic proteins, antisense oligonucleotides, viral vectors, and other modalities with CNS delivery/targeting properties
  • Establish in vitro assays to assess CNS delivery/targeting properties of therapeutic proteins, antisense oligonucleotides, viral vectors, and other modalities
  • Co-Lead research efforts on specific projects involving novel BBB targets or other modalities

Who You Are Why Biogen?

Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us as a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients’ lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.

Required Skills
  • PhD in biochemistry, molecular and cellular biology, neuroscience/neuropathology or a related field
  • 0-3 years of postdoctoral experience
  • Extensive experience with in vivo animal handling including transcardial perfusion, tissue extraction and dissection (brain, spinal cord and other tissues) of rodents
  • Experience in handling and working with large molecules
  • Ability to establish in vitro assays such as cellular binding using ELISA/MSD and FACS; internalization assays using cellular imaging and other relevant techniques, as well as transcytosis assays

Preferred Skills
  • Industry experience preferred
  • Familiarity with immunohistochemistry
  • Knowledge in BBB field and CNS delivery technologies including receptor-mediated transcytosis or viral-delivery technologies

Additional Information

Biogen’s US Alzheimer’s Franchise is looking to recruit proven and ambitious sales achievers with at least five years of experience in pharma, specialty, hospital, med device/capital equipment, and/or biotech sales.
In this field-based, specialty sales representative position you will be called upon to sell our products with key stakeholders in the Alzheimer’s Disease community: including Neurologists and allied health professionals.