Discovery Biologics, Protein Sciences - Mass Spectrometry - Scientist

Job Description

Our Research & Development Division is seeking to recruit a scientist with experience in Biologics characterization (including antibody-drug conjugates - ADCs) to join the Protein Sciences Department in South San Francisco- CA. The position will be hands-on at the bench and will report to the mass spectrometry group leader.

  • Perform mass spectrometry-based analysis for biologics in support to Protein Sciences core activities.
  • Perform analytical routines for LC/MS systems maintenance, including calibration, system suitability, and troubleshooting.
  • Handle OEB4 and OEB5 compounds safely by following Environment, Health, and Safety protocols and procedures.
  • Manually aliquot and label vials containing purified proteins for storage
  • Prepare solutions and buffers following established SOPs.
  • Document data as needed in an electronic lab notebook.

Minimum Requirements

Education Requirement:
  • An MS or BS degree with 1-3 years of relevant laboratory bench experience.

Experience/Skills Requirement:
  • Have knowledge and hands-on experience with mass spectrometry-based analytical characterization of biologics.
  • Must be highly organized and have good communication and written skills.
  • Must have attention to details and the ability to follow written procedures.

Preferred Qualifications:
  • Recent experience in the biopharmaceutical industry is strongly preferred.
  • Good understanding of various analytical methods for protein characterization such as SEC, CE-SDS, HIC, RP-HPLC.
  • Hands-on experience with Agilent QTOF/TOF, and high-resolution Q-Exactive mass spectrometers platforms;
  • Experience with software platforms for intact mass deconvolution, including BioConfirm and/or Genedata Expressionist.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science" that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are ...

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for ...

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.


In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

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Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:

No relocation

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Travel Requirements:

Flexible Work Arrangements:


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Requisition ID:R138629