Senior Scientist

Job Description

Our company is a global health care leader with a diversified portfolio of prescription medicines, vaccines and consumer health products, as well as animal health products. Today, we are building a new kind of healthcare company - one that is ready to help create a healthier future for all of us.

Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of people like you. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. As part of our global team, you'll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career.

We are seeking a highly motivated Senior Scientist to join the Department of Pharmacokinetics, Pharmacodynamics and Drug Metabolism (PPDM) in the area of Regulated Vaccine Immunogenicity Bioanalytics. The primary role of the successful candidate will be to design and develop cellular immunology-based preclinical and clinical assays for our Vaccines pipeline. The incumbent will contribute with limited supervision to all aspects of assay development, qualification/validation, technology transfer, and/or troubleshooting. Preferably, the successful candidate should have a proven track record for developing assays capable to meet Regulatory expectations for validation and line of sight for life-cycle maintenance. The candidate should be current on state-of-the art technologies and is expected to champion evaluation of new technologies and optimize processes. Providing expert technical representation on multidisciplinary teams will be expected.

Responsibilities:
  • Provide scientific input to the design and execution of ligand binding assays such as ELISA and/or cell-based assays such as Luciferase report assays,
  • Responsible for the execution of method development, qualification/validation, troubleshooting and/or pre-clinical/clinical sample analysis as needed.
  • Contribute to the assessment and implementation of new analytical technologies.
  • Serve as an internal subject matter expert on developed assays.
  • Accountability for the generated data


Education:
  • BS degree in a relevant discipline with 7+ years experience or a MS with 4+ years, or a PhD with some experience


Required Skills:
  • Critical thinking and good trouble-shooting skills
  • Comply with applicable Guidance and Regulations. Contribute to assay protocol and qualification/validation report preparation. Address QA findings and observations.
  • Adherence to basic safety procedures in a BSL2 laboratory.
  • Good verbal and written communication
  • Ability to follow procedures and thoroughly document experiments
  • Communicate results effectively in presentations to stakeholders in partner organizations or at external scientific meetings, to write technical reports, and to participate on cross-functional teams


Preferred Skills:
  • Experience with in vitro primary immune cell functional assays such as PBMC isolation, ELISpot, or multi-color flow cytometry
  • Knowledge and expertise in assay qualification/validation and troubleshooting of cell-based assays and/or ligand-binding assays.
  • Familiarity with liquid handlers and other automation platforms for sample preparation and assay process is preferred.
  • Familiarity with Regulated Bioanalysis and Good Laboratory Practice (GLP/GCLP) is strongly desired.
  • Experience with GxP as it applies to regulated bioanalysis


Your role at our company is integral to helping the world meet new breakthroughs that affect generations to come, and we're counting on your skills and inventiveness to help make meaningful contributions to global medical advancement.

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we "follow the science" that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are ...

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for ...

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization.

NOTICE FOR INTERNAL APPLICANTS

In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.

If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

For more information about personal rights under Equal Employment Opportunity, visit:

EEOC Poster

EEOC GINA Supplement​

OFCCP EEO Supplement

Pay Transparency Nondiscrimination

We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:
Regular

Relocation:
Domestic

VISA Sponsorship:
No

Travel Requirements:

Flexible Work Arrangements:

Shift:

Valid Driving License:

Hazardous Material(s):

Number of Openings:
2

Requisition ID:R133464