Engineer I / Associate Scientist II, Cell Culture Development

Job Description

About This Role

This position will focus on the development of highly productive and robust cell culture processes through classically and statistically designed experiments. The candidate’s goals will be to increase process robustness and productivity through comprehensive understanding of levers important to mammalian cell culture involving multiple CHO cell lines producing a variety of novel or biosimilar therapeutics including but not limited to monoclonal antibodies, fusion proteins and other complex biologics. These activities can include clone screening, early and late stage scale-up process optimization, process robustness studies and process characterization. A major component of the role will involve conducting and documenting laboratory bioreactor experiments with a focus on process definition and understanding, experimental design and troubleshooting, and data analysis. The ideal candidate will be able to work collaboratively with pilot scale and tech transfer teams for execution of development projects. In addition, the ideal candidate will contribute to improving laboratory process workflows, making laboratory work more efficient and with greater impact. The right candidate may also contribute to technology innovation projects that utilize multi-omics tools to gain deeper understanding of biological processes, development/optimization of continuous manufacturing and evaluation of alternative hosts for low cost protein production. Candidates must be strong team players, have an ability to collaborate effectively on complex projects, and have an affinity for working in a laboratory environment.

WhatYou’llDo
  • Perform and document experiments at bench-scale (shake flasks, AMBR, 3L reactors, etc.) to support development of mammalian Cell Culture processes for recombinant protein production
  • Contribute to experimental planning based on experience and literature searches
  • Collaboratively work with team members to ensure lab experiments are well-planned and executed
  • Perform data analysis and troubleshooting of experiments and lab equipment
  • Document development work in concise reports and provide project updates via oral presentations
  • Support lab maintenance tasks, lab harmonization and workflow optimizations.
  • Support new technology evaluations and innovation projects and present findings in form of scientific publications and at external conferences.


Who YouAre

We are seeking a highly motivated and creative individual to join our Cell Culture Development team. This position provides an exciting opportunity to develop robust, highly productive cell culture processes and contribute towards new technology and innovation projects for production of recombinant protein biologics.

Qualifications

Required Skills
  • Bachelor's degree in a scientific discipline, such as Biochemistry, Chemical Engineering, Chemistry, or related Biological Sciences.
  • 0+ years of relevant experience.

Preferred Skills
  • Knowledge of or technical experience in mammalian cell culture/ biotechnology related development including aseptic operations, cell biology, biochemistry, analytical techniques, and bioreactor operations.
  • Familiarity working with complex laboratory operations, instrumentation and control systems.
  • Excellent verbal and written communication skills.




Additional Information

Biogen’s US Alzheimer’s Franchise is looking to recruit proven and ambitious sales achievers with at least five years of experience in pharma, specialty, hospital, med device/capital equipment, and/or biotech sales.
In this field-based, specialty sales representative position you will be called upon to sell our products with key stakeholders in the Alzheimer’s Disease community: including Neurologists and allied health professionals.

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