Senior Manager, HEOR, Lung Cancer


The Senior Manager, Health Economics & Outcomes Research - Lung Cancer will be a member of the PHI Renal Lung Immuno Oncology (RLIO) team. The focus on Lung will be for both Lorbrena and in support of the launch of and commercialization of Braftovi-Mektovi for BRAF+ NSCLC. While the role will have primary focus in US, the Senior Manager will be part of a US/Global team and will have exposure to Global projects.

This role directly impacts the ability to achieve business objectives in the US by providing strategic guidance, executing, and communicating evidence generated to demonstrate the value of the approved uses of Lorbrena and Braftovi-Mektovi in Lung Cancer.

The Health Economics & Outcomes Research (HEOR) Sr Manager will work in a closely aligned fashion with the US Medical Affairs, Field Medical Directors, the Cross -Functional Leadership Team (CFLT) and other functional areas within PHI as well as the brand team to ensure there is a single and coordinated view on strategy and delivery from PHI to US Lung Cancer stakeholders.

  • Manage execution of clinically relevant and scientifically valid, HEOR studies and projects (including non-interventional studies, registries, etc.) in alignment with the global HEOR strategy catered to diverse stakeholders (regulators, payers, patients, physicians and policy makers)
  • Work closely in collaboration with US Medical Affairs and Field Medical colleagues to develop evidence and tools that demonstrate the value of our medicines to healthcare decision makers
  • Develop and update economic models and dossiers based on new insights and data: providing support for pathway submission in US, demonstrate health care resource utilization to integrated systems, support benefit to practice economics
  • Provide relevant input into selection of patient population and comparators within clinical trials to enable demonstration of robust incremental clinical value over standard of care that can facilitate optimal patient access.
  • Coordinate the selection, related analyses, interpretation and communication of Patient Reported Outcomes (PRO) measures as appropriate for assigned clinical trials, registries, and prospective real-world studies.
  • As required, support the timely development of post launch deliverables including update of value dossiers ( AMCP), economic models, and innovative tools to successfully support reimbursement.
  • Support the coordination of input from US cross functional team on evidence needs and ensure that the input is appropriately incorporated to support demonstration of product value and optimize patient access of formularies, pathways and therapeutic utilization practices.
  • Execute studies to generate evidence to support brand competitive differentiation and value proposition.
  • Collaborate with US cross functional team, conduct training on economic models and support local model adaptations and updates throughout the product life cycle.
  • Support appropriate data dissemination plans and communicate in a timely manner evidence generated to various stakeholders via publications and conference presentations.

  • Minimum: Masters degree (MSc, MPH) in health services research, pharmacy administration/pharmaceutical policy, public health or epidemiology. Doctoral degree (PhD, DrPH, ScD) in relevant fields preferred.
  • Minimum 3-5 years' experience in health outcomes and related fields and preferably a few years in health economics and/or outcomes research teams in a global pharmaceutical company.
  • Past experience with early development, clinical trials, patient reported outcomes and real-world study design and implementation is desirable
  • Experience working with US stakeholders required
  • Demonstrated understanding of fundamental health services research methods (e.g., health economics, patient reported outcomes, research study design, database analyses, epidemiology and statistics) and external environmental trends influencing health care/pharmaceuticals in key markets worldwide
  • Demonstrated ability to manage multiple projects involving complex processes, significant budget, competing deadlines and rapidly shifting priorities
  • Excellent interpersonal skills required; ability to understand and respond to multiple internal and external customers and influence in a matrix environment
  • Excellent oral and written English communication skills required
  • Strong project management abilities (contracting, budgeting, vendor management) essential
  • Skilled in functioning within a matrix organization where managing through influence is required

Other Job Details:

Last Date to Apply for Job: November 5th, 2021

Additional Location Information: New York, NY; Collegeville, PA; US - Remote; Canada - Remote


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