Assoc. Scientist III / Sr. Assoc. Scientist, DMPK

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Job Description

About This Role

In this role you will develop and conduct ligand binding assays (LBA) to enable discovery and develop innovative therapeutics for people living with serious neurological and neurodegenerative diseases. This is part of a dynamic and friendly team with functions of in vivo PK as well as bioanalysis and biodistribution of new modalities including antibody and gene therapy drug candidates.

What You’ll Do
  • Develop and conduct LBA on large molecule biotherapeutics for non-clinical and possible clinical studies across Biogen’s pipelines
  • Provide high quality bioanalytical support with a focus on large molecule quantification by LBA and other pertinent-platform technologies
  • Deliver and present the experimental results to cross-functional and DMPK teams
  • Provide scientific monitoring and guidance on outsourcing studies for the method transfer, development, troubleshooting, qualification, validation and report
  • Write and review bioanalytical study protocols and reports that are suitable for inclusion in registration dossiers (IB, IND/IMPD, BLA).

Why Biogen?

Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us as a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients’ lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.

Who You Are

You are passionate about bioanalysis and characterization of new modalities such as antibody and antibody-anti-sense oligonucleotide conjugate. You love learning new technological skills and working through collaboration.

Required Education/ Skills
  • A BS in Pharmaceutical Sciences, Biochemistry, Chemistry, or a related field with at least 5+ years’ experience, or a MS with at least 2+ years’ industry experience
  • Knowledge and experience in conducting ligand binding assays on large molecule biotherapeutics for both non-GLP and GLP studies
  • Hands-on experience with assay execution, method development, validation, and troubleshooting of the LBA quantification

Preferred Skills
  • Experience in quantification of anti-drug antibody (ADA) or biomarkers by LBA or LC-MS
  • Experience in studying CNS drug disposition and blood-brain barrier

Additional Information

Biogen’s US Alzheimer’s Franchise is looking to recruit proven and ambitious sales achievers with at least five years of experience in pharma, specialty, hospital, med device/capital equipment, and/or biotech sales.
In this field-based, specialty sales representative position you will be called upon to sell our products with key stakeholders in the Alzheimer’s Disease community: including Neurologists and allied health professionals.