Process Development Associate Scientist or Senior Associate

Amgen Pre-Pivotal Drug Substance Technologies Organization is seeking a Process Development Associate or Senior Associate responsible for cell line development in support of advancing Amgen pre-clinical large molecule pipeline. We are particularly interested in candidates with experience in mammalian cell culture, molecular biology, vector construction and design, single cell cloning and high-throughput clone screening .

Job Responsibilities:
  • Design, execute and characterize manufacturing cell lines, including DNA cloning, transfection, selection, single cell cloning and clone scale up, clone screening and cell banking
  • Support cell engineering and characterization activities
  • Analyze and interpret data, maintain laboratory notebooks, and generate written reports
  • Generate relevant data towards authoring of regulatory submissions,publications, and patent applications
  • Communicate project updates, solve complex technical problems, participate, and present scientific data in meetings
  • Evaluate and develop innovative technologies to improve expression, accelerate timelines, and improve efficiency
  • Work closely in a team environment, collaborating with various colleagues in process development, discovery, as well as interact with regulatory and quality experts in support of global regulatory filings

Basic Qualifications:
  • Master's degree, or
  • Bachelor's degree with 3 years of relevant experience

Preferred Qualifications:
  • Master's degree in life science, or related fields with 3 years of relevant scientific experience
  • Hands on experience in mammalian cell culture with a focus on recombinant protein production and excellent aseptic techniques
  • Experience with DNA cloning, vector construction and design, advanced molecular biology techniques, and optimizing gene expression constructs
  • Experience with single cell cloning and high-throughput screening
  • Strong understanding of all aspects in cell line development, bioprocess development and manufacturing of biotherapeutics
  • Strong scientific understanding of recombinant protein expression, gene editing and cell engineering technologies as well as the ability to explore and develop new technologies and approaches
  • Excellent organizational skills with the ability to design and troubleshoot experiments with minimal supervision
  • Demonstrated ability to deliver on timelines and adapt to rapid changes in project priorities.
  • Strong attention to detail with the ability to multi-task and handle multiple responsibilities simultaneously
  • Advanced scientific/technical reading/writing skills, advanced analysis skills, ability to collaborate and work in team environment
  • Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.