Scientist - Computational Biology


You've earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you've worked hard to acquire and the passion you already have. At Amgen, our shared mission-to serve patients-drives all that we do. It is key to our becoming one of the world's leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role.

Scientist- Computational Biology

The Clinical Biomarkers & Diagnostics (CBD) department at Amgen is looking for an experienced and highly motivated data ingestion team lead with expertise in biomarker data ingestion and harmonization and knowledge in clinical data and biomarker assays. This role will operate within a multi-disciplinary setting, working closely with assay validation, biomarker scientists, computational biology, data scientists, operational leads to establish standards, infrastructure and process for the ingestion and QC of biomarker data.


What you will do

Let's do this. Let's change the world. In this vital role you will
  • Own the development, maintenance of biomarker data ingestion pipeline, and develop additional code to ingest any new types of biomarker data, perform QC, and reliably integrate with clinical data.
  • Serve as team lead for all data ingestion activities within Clinical Biomarkers and Diagnostics (CBD) and work with external vendors, partners in study management and operational leads
  • Define acceptance standards for data generated using various diagnostic technologies, document acceptance standards, dynamic ranges, controlled terminology, socialize them and communicate to partners
  • Generate analysis ready data bundles with quality control for active programs in a timely manner
  • Design database schemas for efficient data storage
  • Document ETL process, maintain data dictionaries, controlled terminology and communicate to partners
  • Develop standard methodologies for pipeline development, data integration, data management and reproducibility.
  • Provide training for new team members and manage other team members' daily activities to complete given task on time and ensure quality of work
  • Attend meetings as necessary, communicate pro-actively with team members on biomarker data ingestion activities, present work in team meeting and other forums regularly



What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a go-getter with these qualifications.

Basic Qualifications

Prior experience working with clinical datasets is a requirement.

Master's degree and 2 years of scientific/clinical development experience


Bachelor's degree and 4 years of scientific/clinical development experience

Preferred Qualifications

  • Bachelor's or Master's degree in Bioinformatics, Computational Biology, Mathematics, Statistics, Computer Science
  • A working knowledge of platforms and readouts utilized for the assessment of clinical biomarkers including flow cytometry, IHC, NGS, immunoassays, imaging and transcriptional profiling assays
  • Programming experience in scripting languages such as Python & R, using version control, Gitlab and continuous integration environments
  • Experience with bioinformatics pipeline development, software development cycle
  • Experience with snakemake, airflow, nextflow and database management
  • Strong written and oral communication skills, self-motivation, independence and leadership.


Some of the vast rewards of working here

As we work to develop treatments that take care of others, so we work to care for our teammates' professional and personal growth and well-being.
  • Full support and career-development resources to expand your skills, enhance your expertise, and maximize your potential along your career journey
  • A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
  • Generous Total Rewards Plan-comprising health, finance and wealth, work/life balance, and career benefits-with compensation and benefits rated above 4 stars (out of 5) on Glassdoor

Apply now

for a career that defies imagination

Objects in your future are closer than they appear. Join us.

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request an accommodation.

Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.

Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.