Sr. Manager, HEOR, Abrocitinib


The Health Economics & Outcomes Research (HEOR) Sr. Manager is responsible for development and execution of high quality HEOR strategic efforts to support optimal reimbursement and access of Abrocitinib (Cibinqo), a new treatment for moderate to severe atopic dermatitis that will launch globally in late 2021. This role directly impacts the ability to achieve business objectives on a global basis by providing strategic guidance and robust evidence development relevant to achieve optimal global patient access by demonstrating the value of abrocitinib.

The HEOR Sr. Manager will work in a closely aligned fashion with the full team to ensure there is a single and coordinated view on strategy and delivery from PHI to the I&I business. The Sr. Manager will collaborate with Global medical, commercial, field, and other cross-functional teams to develop and implement health outcomes research strategies to support assets globally. The Sr. Manager will support the HEOR lead for the Abrocitinib program.

  • Support the development of the Health Economics & Outcomes Research (HEOR) strategy to support the value of Abrocitinib in close partnership with PHI and the cross-functional team.
  • Lead the execution of HEOR studies and projects in alignment with the global HEOR strategy and demonstrate the value proposition for abrocitinib. This may include some or all of the following:
    • Lead the timely development of launch and post launch deliverables including global value dossiers (GVDs), evidence blueprints, economic models, and innovative tools to successfully support global launch and post-launch reimbursement and access requirements in conjunction with the regions/countries.
    • Develop real world evidence generation strategies and execute studies (e.g., burden of illness, comparative effectiveness studies).
    • Incorporate humanistic and economic endpoints into clinical trials across all phases of product development to build comprehensive trial-based evidence in line with overall medical strategy for the assets and to ensure global reimbursement and access requirements. Provide strategic input in the selection of relevant patient population and comparators within clinical trials to enable successful negotiations, reimbursement, and appropriate patient access with global payer and regulatory decision makers.
    • Develop and validate new Patient Reported Outcomes measures, as appropriate, for inclusion across clinical trials, registries, and prospective real world studies.
    • Lead the development of appropriate data dissemination plans and communicate evidence generated via publications and conference presentations.
  • Identify opportunities to partner with external customers to conduct HEOR projects in support of asset strategies
  • Lead the coordination of input from local country teams on evidence needs and ensure that the input is appropriately incorporated to develop and integrated evidence strategy to support global market access needs at time of launch.
  • Collaborate with local health and value affiliates and enable local model adaptations and updates throughout the product life cycle.
  • Provide content guidance in reimbursement (re)negotiations.
  • Assess, synthesize, and interpret relevant literature and communicate findings to internal and external stakeholders
  • Execute and manage research projects with external collaborators/vendors to ensure timely completion and quality of deliverables as well as budget/legal compliance.


Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
  • Minimum Masters degree (MSc, MPH) in health services research, public health, epidemiology, or health economics with a preferred Doctoral degree (PhD, DrPH, ScD) in health services research, public health, epidemiology, or health economics.
  • Minimum 4 years' experience in health outcomes and related fields, 2 of which are as part of global health economics and/or outcomes research teams in a pharmaceutical company.
  • Strong working knowledge of the technical and methodological aspects of registries and observational study design and implementation. Capable of managing registry and non-interventional study projects.
  • Strong methodological skills (study design, data analysis and interpretation) in clinical trials, epidemiology, or health services research is required
  • Understanding of Health Economics and Quality of Life
  • Knowledge and experience in the I&I therapeutic area is preferred
  • Experience with HTA organizations such as NICE, SMC, PBAC desirable
  • Excellent interpersonal skills required: ability to understand and respond to multiple internal and external customers
  • Excellent oral and written English communication skills required
  • Strong project management abilities (contracting, budgeting, vendor management) essential. Demonstrated ability to manage multiple projects involving complex processes, significant budget, competing deadlines and rapidly shifting priorities
  • Ability to influence key members of medical and commercial teams constructively and without conflict
  • Skilled in functioning within a matrix organization where managing through influence is required

Other Job Details:

Last Date to Apply for Job: December 8th, 2021

Additional Location Information: New York, NY; US - Remote; Europe - Remote; Canada - Remote


Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

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