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Job Details
MD Anderson Cancer Center
Research Investigator - Genomics
The primary purpose of the Research Investigator position is to apply technical expertise and experience to coordinate, design, and carry out cancer research projects while following lab standard operating procedures. We are seeking a well-organized, highly motivated professional to support the research Cancer Genomics Laboratory to support the high throughput sequencing pipeline for Moon Shots projects. The successful candidate will use cutting-edge technologies and machinery for cancer cell genome characterization and will have solid molecular Biology experience and demonstrate solid experience with LIMS system.
Key Functions
- Lead execution of DNA/RNA sequencing, array-CGH, EA and genotyping experiments in a timely fashion.
- Ability to comprehensively perform all areas of Next Generation Sequencing, including but not limited to sample preparation from difficult analytes, sample QC-ing, sample clustering on the cBot.
- Operation of the Illumina NGS instruments, including running, troubleshooting and monitoring data quality output and implement corrective measures.
- Troubleshooting sequencing protocols to implement SOPs to be used by the production team.
- Developing SOPs for one-off sequencing projects that accommodates low-quality, low-input DNA/RNA from FFPE tissue.
- Design target enrichment including SureSelect, ChIP, and other technologies. Adapt to new technologies and find solutions to related academic programs.
- Reads literature and confers with superiors regarding new procedures and modify them according to the needs of the project.
- Ability to search and review the scientific literature for the purpose of developing SOP's
- Proficiently use standard MS office products and willing to learn the LIMS systems employed by the laboratory.
- Responsible for maintaining an adequate level of reagents for Next Generation Sequencing in the lab.
- Plans training and research work activity for assigned laboratory and research personnel.
- Timely laboratory sample tracking with required documents. Overall QA right along data generation pipeline. Generate standard operating procedures.
- Compiles, writes and submits project results to superiors.
- Provides supervision, special training to technical personnel and/or highly technical work in medical and related research projects.
- Other duties as assigned.
Core Competencies
- IC - Coach & Develop:
- Assess strengths and development needs of employees;
- Provide challenging development opportunities; and
- Provide relevant, timely feedback; mentor others.
- IC - Build Relationships:
- Initiate, develop, and manage relationships and networks; and
- Show sincere interest in others and their concerns.
- IC - Provide Direction:
- Provide clear direction and priorities toward a common vision;
- Clarify roles and responsibilities for employees; and
- Promote empowerment.
Working Conditions
| This position requires : | Yes | No |
| Working in Office Environment | | X |
| Working in Patient Care Unit (e.g. Nursing unit; outpatient clinic) | | X |
| Exposure to human/animal blood, body fluids, or tissues | X | |
| Exposure to harmful chemicals | X | |
| Exposure to radiation | X | |
Physical Demands
Indicate the time required to do each of the following physical demands:
| | Time Spent | ||||
| Never 0% | Occasionally 1-33% | Frequently 34-66% | Continuously 67-100% | ||
| Standing | | | X | | |
| Walking | | X | | | |
| Sitting | | X | | ||
| Reaching | | X | | | |
| Lifting/Carrying | |||||
| | Up to 10 lbs | | X | | |
| | 10lbs to 50 lbs | X | | | |
| | More than 50 lbs | X | | | |
| Pushing/Pulling | |||||
| | Up to 10 lbs | | X | | |
| | 10lbs to 50 lbs | X | | | |
| | More than 50 lbs | X | | | |
| Use computer/keyboard | | X | | ||
EDUCATION:
Required: Bachelor's degree in one of the natural sciences or related field.
Preferred: Master's degree in genetics or genomics.
EXPERIENCE:
Required: Five years of experience in scientific or experimental research work. With preferred degree, three years of required experience.
Preferred: The ideal candidate will have the following:
* Computer experience working with large data sets.
* Must be highly motivated, reliable, responsible, well organized and a careful record keeper with good attention to details.
* Excellent communication skills are required as well as the ability to work well in a collaborative and interdisciplinary team environment.
It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. [Register to View] Information
- Requisition ID: 152423
- Employment Status: Full-Time
- Employee Status: Regular
- FLSA: exempt and not eligible for overtime pay
- Work Week: Days
- Fund Type: Soft
- Work Location: Onsite
- Pivotal Position: Yes
- Minimum Salary: US Dollar (USD) 47,500
- Midpoint Salary: US Dollar (USD) 59,500
- Maximum Salary : US Dollar (USD) 71,500
- Science Jobs: Yes