Investigator, Synthetic Lethality (Upper Providence, PA)
Are you energized by a challenging role in the Oncology Synthetic Lethality Research Unit, where scientific demand is driving team growth? If so, this Investigator, Cancer Biology role would be a great opportunity to consider.
This role will provide you the opportunity to lead key activities to progress your career. These responsibilities include some of the following:
- Discover and develop novel oncology drugs with a clear genetic relationship to cancer.
- More specific activities include the prosecution of discovery programs from target validation through clinical candidate nomination. Studies will also involve identification and development of pharmacodynamic markers and assays to be used in non-clinical and clinical studies.
- PhD in Cell Biology, Molecular Biology, Biochemistry, Pharmacology, or related life sciences field with strong scientific background in cell biology and oncology and a minimum of 3 years of post-graduate research experience in cancer biology
- One or more years of experience developing and implementing new scientific strategies in the field of tumor biology
- One or more years of experience in design, conduct, and analysis of cellular and molecular biology experiments independently
If you have the following characteristics, it would be a plus:
- Extensive cell biology experience and expertise is expected and experience in cell-based assay development is preferred
- Deep knowledge in DNA damage response (DDR), DNA damage repair pathways, genome instability and replication stress is strongly valued
- Working knowledge of -omic methods (e.g., sequencing, transcriptomics, and/or proteomics) and databases (e.g., Sanger, CCLE, Oncomine and/or similar other databases) is preferred
- Demonstrated ability to work effectively in a team/matrix environment
- Excellent written and verbal communication skills with a strong background in cancer biology reflected in peer reviewed publications
- Strong organizational skills and the ability to manage multiple priorities in a matrix environment.
We’re combining the power of genetic and genomic insights into what causes disease, with the speed and scale of artificial intelligence and machine learning (AI/ML) to make better predictions about who a treatment might work for, and why. We believe this powerful combination of data and technology holds the key to fundamentally transforming medical discovery for the better, improving R&D success rates and shaping how even the most challenging diseases, like neurological conditions and cancer, can be both prevented and treated.
In 2021 we delivered four major product approvals: Cabenuva for HIV, Jemperli for endometrial cancer, Xevudy for COVID-19 and Apretude, our new long-acting medicine for HIV prevention.
Find out more:
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.
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