Research Scientist, Immunology & Cellular Analysis, Analytical R&D
Site Name: USA - Maryland - Rockville
Posted Date: Mar 6 2023
Are you interested in assisting in the design and development of analytical methods to support product and process development? If so, this Scientist in Analytical Research and Development could be an ideal opportunity to explore.
As a Research Scientist, you will be responsible for participating in the development of analytical methods in the bioassay area to support process development, manufacture, and product understanding of new candidate mRNA or protein vaccines.
The lease for Rockville Vaccines site, where this role is currently being recruited, will expire by Q2 2026 and we have decided not to renew the lease. Consequently, this lab-based role will be relocated to Boston, Massachusetts in 2025.
This role will provide you the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:
- Immunol and Cell-based assay development for vaccine lot characterization and release, including assay optimization and qualification for CMC support.
- Collaborate with other Technical R&D functional groups, coordinate and perform sample testing to support process development and formulation development.
- Maintain laboratory notebooks in a timely manner, document experimental results under GSP (Good Scientific Practice)
- Write and review standard operation protocols, study reports, and relevant sections of regulatory filings.
- Design experiment, analyze and interpret data independently, present findings to the department and project teams.
We are looking for professionals with these required skills to achieve our goals:
- Ph.D. in Immunology, Virology, Cell Biology or related field with a minimum of 2-5 years of postdoctoral experiences.
- Experiences for cell culture and cell-based assay development.
- Basic immunological and molecular biology assay skills: Flow cytometry, ELISA, RNA expression and Immunol staining, etc.
- Thorough knowledge of the molecular pathways involved in the activation of the innate and/or adaptive immune responses.
- Proficient in multi-color flow cytometer, such as Symphony, Fortessa, and Canto LSR, et al.
- Skilled in flow cytometry panel design and flow data analysis using FlowJo or related software.
- Experience with in vitro immune assays with primary cells, such as DC differentiation, T cell activation, B cell activation and innate immune assays.
- Experiences in immune assay development using ELISA, AlphaLisa, Gyros, Luminex, Elispot, and High Content Analysis technologies.
- Experiences in Single Cell Analysis technique and data analysis.
- Industrial experiences in analytical assay development including assay optimization and qualification.
- Strong problem-solving skills and attention to detail.
- Strong oral and written communication skills and a team player in a matrix environment.
We’re combining the power of genetic and genomic insights into what causes disease, with the speed and scale of artificial intelligence and machine learning (AI/ML) to make better predictions about who a treatment might work for, and why. We believe this powerful combination of data and technology holds the key to fundamentally transforming medical discovery for the better, improving R&D success rates and shaping how even the most challenging diseases, like neurological conditions and cancer, can be both prevented and treated.
In 2021 we delivered four major product approvals: Cabenuva for HIV, Jemperli for endometrial cancer, Xevudy for COVID-19 and Apretude, our new long-acting medicine for HIV prevention.
Find out more:
GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.
Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.
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At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve.
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