Job was saved successfully.
Job was removed from Saved Jobs.

Job Details

GlaxoSmithKline (GSK)

Principal Programmer



Full Time

On Site


Collegeville, Pennsylvania, United States

By applying to this role we will also consider you application for our other open roles in our Programming department. If you would not like to be considered for multiple opportunities please flag to our recruitment team

Clinical Programming at GSK

GSK Clinical Programming brings together some of the most talented minds to engage in advanced data analytics, principles of data science, and developing new computational tools to support innovative research and develop novel therapies. We serve five key therapeutic areas: HIV, Immunology, Infections Disease, Oncology, Respiratory, and Vaccines, and offer unlimited growth opportunities and exciting career paths for a wide range of experience levels.

Your Role

The Principal Programmer role supports all aspects of programming activities and engages in study lead activities under supervision. Senior programmers are expected to be subject matter experts and be able to mentor and train junior team members and new hires. They are technically strong, possess good communication and time management skills, are problem solvers, be able to engage in study lead responsibilities, and are willing to mentor junior programmers and new hires.

Principal Programmer at GSK will support the planning and execution of the programming activities for GSK clinical trials. They will be accountable for creating, verifying, and documenting analyses of clinical data while adhering to study protocols, analysis plans and GSK / industry standards. They will also be able to lead certain aspects of a study under supervision. Principal Programmer will be expected to participate in capabilities and non-project initiatives, present at internal forums, and learn new programming languages. They will also interact with non-programming team members and participate in core study team meetings under supervision.

In this role you will

  • Demonstrates proficiency in developing, QCing, and debugging complex code and macros with minimal supervision
  • Identifies gaps in current programming best practices and offer suggestions
  • Understands the management of programs, including change control, and their importance
  • Ensures adherence to standards and has an awareness of evolving standards, both internal and external
  • Keeps an awareness of departmental strategies and initiatives
  • Provides input to strategic planning, where requested and under supervision, which may be shared with stakeholders
  • Anticipates problems related to assigned work or areas of expertise and able to implement solutions, proactively seeking input from colleagues as needed
  • Provide innovative solutions to solve more complex problems relating to own work
  • Contributes changes to programming best practices.
  • Applies standard processes to tasks, ensuring that deliverables are accurate, high quality and met according to agreed timelines
  • Understands GxP, ICH requirements, internal processes and external regulations that govern drug development (where applicable)
  • Quickly understands and implements internal processes and standards in assigned work
  • Performs Quality Control (QC) of other people’s work (under supervision)
  • Performs required archiving activities and understands the implications of accurate and timely documentation
  • Anticipates compliance, quality or governance issues and proposes solutions to achieve resolution
  • Demonstrates effectiveness in oral and written communications, ability to express ideas, and incorporate feedback to produce quality deliverables
  • Informs supervisor and matrix leaders of appropriate progress and activities
  • Able to explain technical approaches to peers and non-technical colleagues/settings
  • Delivers presentations with clarity in internal forums and/or external professional industry meetings
  • Works with multi-disciplinary teams (under supervision)
  • Uses networking skills to collaborate with peers or non-programming stakeholders
  • Represents function and/or GSK as part of a team for external organizations

Closing Date for Applications: until filled

Please take a copy of the Job Description, as this will not be available post closure of the advert.
When applying for this role, please use the ‘cover letter’ of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process. If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements, please contact 0[Register to View] . This will help us to understand any modifications we may need to make to support you throughout our selection process.


Why you?

Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

  • A BSC or BA (or equivalent) in Mathematics, Statistics, Computer Science or related subject
  • Experience or knowledge with using one or more programming languages, such as R, Python, Spotfire, S-Plus, and/or SAS

Preferred Qualifications & Skills:

If you have the following characteristics, it would be a plus:

  • MSc or PhD (or equivalent) in Mathematics, Statistics, Computer Science or related subject preferred
  • Familiarity with CDISC standards and its application
  • Experience with submission activities is preferred
  • Intermediate to advanced understanding of the end-to-end clinical trial process
  • Strong understanding of the purpose and application of key clinical documents
  • Effective written, verbal communication skills
  • Basic experience with representing programming function in cross-functional meetings, initiatives, and working groups.
  • Some experience with training and mentoring junior programmers
  • Basic knowledge of Microsoft Office software (MS Word, Excel, PowerPoint, Outlook)

Why GSK?

We’re combining the power of genetic and genomic insights into what causes disease, with the speed and scale of artificial intelligence and machine learning (AI/ML) to make better predictions about who a treatment might work for, and why. We believe this powerful combination of data and technology holds the key to fundamentally transforming medical discovery for the better, improving R&D success rates and shaping how even the most challenging diseases, like neurological conditions and cancer, can be both prevented and treated. In 2021 we delivered four major product approvals: Cabenuva for HIV, Jemperli for endometrial cancer, Xevudy for COVID-19 and Apretude, our new long-acting medicine for HIV prevention.

Find out more:

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-[Register to View] (US Toll Free) or +1 [Register to View] (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve.

GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit GSK’s Transparency Reporting [Register to View] site.