Senior Scientist, Neuroscience

Job Description

Our Research Scientists are our Inventors. We identify and target steps in disease mechanisms or pathways that could be inhibited or enhanced. Our goal is to isolate a compound that is effective against a disease target. Using innovative thinking, state-of-the-art facilities and robust scientific methodology we collaborate to discover the next medical breakthrough.

We are seeking a highly motivated and skilled scientist with expertise in molecular biology, Biochemistry and High content Imaging to join our Neuroscience group at our Company's West Point Site. This exciting role will allow a talented scientist the opportunity to support novel target discovery for neurodegenerative diseases. The primary responsibilities include the design and execution of disease-relevant cell culture studies (cell lines and primary neuronal models), biochemical assays and understand mechanism of action using relevant assays.

The candidate will be supporting validation of discoveries using genetic and pharmacological manipulation in relevant systems and will be a part of a collaborative team. The role will also require the ability to independently keep up with relevant scientific literature, implement new technical expertise and assay development, and be an active participant in the scientific dialogue in project meetings and internal/external scientific meetings.

Education Requirements

Degree in Neuroscience | Biochemistry | Pharmacology or Related Discipline

• Bachelor's degree and 4 years of relevant work experience OR

• Master's degree and 2 years of relevant work experience

Experience and Skills

Required

• Cell culture techniques and development of in vitro functional assays

• Molecular biology and imaging assays such as qPCR, Western blot, ELISA, high-content imaging

• Ability to balance collaboration and independence to efficiently design, implement, and interpret critical experiments

• Highly developed verbal and written communication skills

Preferred

• Rodent primary neuronal cultures and iPSC-derived neuronal models

• Neuroscience specific functional molecular biology tools for gene validation, e.g. viral vector mediated knock-down or CRISPR/cas9 methods, viral vector delivered reporter genes

• Proven track record of scientific accomplishment including generating publication quality data and contributing to manuscript or patent preparation

• Demonstrate proficiency in both Neuroscience and Pharmacology

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are …

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization. Together we will continue Inventing For Life, Impacting Lives while Inspiring Your Career Growth.

Invent. Impact. Inspire.

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

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Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

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Requisition ID:R118134