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Job Details

Merck & Co. Inc.

Principal Scientist, Economic & Data Sciences



Full Time

On Site


West Point, Pennsylvania, United States

Job Description

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” and that great medicines can make a significant impact to our world. And we believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

We have an exciting, new opportunity for an Principal Scientist, Economic and Data Sciences to join our team. The preferred location is West Point, PA; alternative locations in USA (Boston, MA, Rahway, NJ, or Philadelphia, PA) and UK (London) are possible.

Economic and Data Sciences is part of our company's Center for Observational and Real World Evidence (CORE). CORE is responsible for generating the evidence to support scientific and commercial value of our company's portfolio to optimize access, reimbursement, and patient outcomes. In collaboration with internal and external partners, CORE Economic and Data Sciences (EDS), provides strategic and technical leadership to enable patient access, measure and quantify the value of our products, inform internal and external decisions, and shape methodology and external health policy and practice. This position will focus on oncology products.


Under the direction of an EDS Director, the Principal Scientist provides strategic development and use of industry-leading predictive and economic models to enhance our understanding of disease and to quantify and communicate the value of our oncology products to patients, providers, and payers.

  • Serve as the CORE EDS lead for one or more value evidence teams to develop health economic, disease, and predictive models to enable business insights for the product.

  • Utilize discovery, real world evidence, clinical trial and published data, and publicly available information and tools to provide economic and integrated models to answer key questions in all phases of drug and vaccine development – Phase I through loss of data exclusivity.

  • Advance the use of integrated quantitative approaches, focusing on economic, disease, and predictive modeling and simulation in partnership with other internal groups and external organizations.

  • Development and maintenance of health quality global health economic models and tools in-house or in collaboration with external vendors to provide critical business insights and fully demonstrate the value of our company’s products.

  • Support and training of EDS models and tools to support country/regional team adaptations and communications with external stakeholders.

  • Dissemination of health economic data via presentations at congresses and publications in scientific journals.

  • Work closely with external collaborators (clinical/economic thought leaders, payer/HTA experts, alliance partners) and internal teams (including those represented on the VEST) to ensure that new methodologies, models and advanced analytics are fully utilized for our products.

  • Maintain awareness of external data, modeling methodologies and IT tools to collaborate across relevant internal stakeholders to enhance our company capabilities in health economic modeling, simulation, and data visualization.

  • Partner in defining and implementing the EDS vision and strategy to develop an innovative, world class Center of Excellence in data science as well predictive and economic modeling.

  • Ensure sharing of work product and relevant best practices across the company enterprise.


  • PhD (preferred) or Masters degree, in Health Economics, Biostatistics, Health Services Research, Actuarial Sciences or a closely related, quantitative field

Required Experience and Skills:

  • Relevant experience in health economics and outcomes research (HEOR) of 5 or more years beyond PhD (or 7 or more years beyond Masters degree)

  • Highly experienced in the economic evaluation of oncology drugs and interventions

  • Strong expertise in the conceptualization, design, development and dissemination of health economic model approaches to enable internal and external decisions

  • Leadership skills, with experience in managing resources and driving implementation

  • Track record of submissions to Health Technology Assessment bodies and research publications in conferences and peer-reviewed journals

  • Strong interpersonal, organizational and communication skills with ability to interact with individuals from a variety of disciplines

  • Understanding of the market access environment and challenges in the US and key international markets

We are a research-driven biopharmaceutical company. Our mission is built on the simple premise that if we “follow the science” that great medicines can make a significant impact to our world. We believe that a research-driven enterprise dedicated to world-class science can succeed by inventing medicine and vaccine innovations that make a difference for patients across the globe.

Who we are …

We are known as Merck & Co., Inc., Kenilworth, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world.

What we look for …

In a world of rapid innovation, we seek brave Inventors who want to make an Impact in all aspects of our business, enabling breakthroughs that will affect generations to come. We encourage you to bring your disruptive thinking, collaborative spirit and diverse perspective to our organization.


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If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.

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We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.

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Merck & Co., Inc., Kenilworth, NJ, USA, also known as Merck Sharp & Dohme Corp., Kenilworth, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

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Requisition ID:R126679