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Health Economics & Outcomes Research, (HEOR) Senior Manager, Inflammation (US Remote)



Full Time

On Site


Los Angeles, California, United States


If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of. Join us.

Health Economics & Outcomes Research (HEOR) Senior Manager, Inflammation (US Remote)Live

What you will do

Let’s do this. Let’s change the world! Reporting to the HEOR Director, the HEOR Senior Manager is accountable for executing on the HEOR Book of Work, strategically aligned with the Access Strategy Lead (ASL), for one or several assets across the life cycle management

The HEOR Book of Work comprises generating global-impact payer-relevant evidence, patient reported outcomes (PRO) and clinical outcomes assessment (COA) strategy, and evidence synthesis. Additionally, the HEOR Senior Manager is responsible to ensure delivery of global core materials to support Health Technology Assessment (HTA) submissions, including the Global Value Dossier (GVD) and economic models

The HEOR Senior Manager role involves execution of deliverables, as well as engaging with internal and external stakeholders.


This role is global, with tactical execution. The HEOR Senior Manager will use their expertise in developing payer-relevant evidence generation, PRO/COA strategy, evidence synthesis and HTA requirements.

The HEOR Senior Manager needs to engage effectively with internal customers to align and support the comprehensive HEOR plan, including the ASL, top-10 countries and cross-functional teams: Evidence Generation Team (EGT), Global Medical Affairs Team (GMAT), Center for Observational Research, Real-world Evidence sub-Team (RWEsT), Global Biostatistical Sciences, US Value Marketing, Medical Value & Access.

HEOR Book of Work:

  • Payer-relevant evidence generation plan and execution of global-impact and United States local-impact studies.

  • PRO/COA strategy

  • Evidence synthesis

  • Global core materials supporting HTA requirements

The HEOR Senior Manager will also engage with vendors and external experts to validate HEOR strategy and technical approach.

The HEOR Senior Manager's main responsibilities include:

  • Translating strategic objectives into concrete execution via HEOR project plan

  • Maintaining strong working relationships with top-10 countries, particularly the United States

  • Ensuring compliance with HTA dossier governance

DAI framework:

  • D: Drives execution of the HEOR Book of Work

  • A: Advices on payer-relevant evidence and HTA strategy to ASL and Global Access Team (GAT)

  • I: Informed of Integrated Access Strategy (IAS) plans


What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The technically astute professional we seek is a collaborative partner with these qualifications.

Basic Qualifications

Doctorate degree and 2 years of health economics & outcomes research experience


Master's degree and 6 years of health economics & outcomes research experience


Bachelor's degree and 8 years of health economics & outcomes research experience


Associate’s degree and 10 years of health economics & outcomes research experience


High school diploma / GED and 12 years of health economics & outcomes research experience

Preferred Qualifications
Health economics training (on the job or academic)
Experience in writing research protocols and publications
Experience in developing payer-relevant evidence, including real-world evidence
Experience in designing PRO/COA strategy
Experience in evidence synthesis (systematic literature reviews, indirect treatment comparisons and meta-analyses)
Strategic and technical understanding of HTA requirements
Experience in developing GVDs and AMCP dossiers
Experience in developing economic models and predictive analytics
Experience in the United States market
Experience in influencing Access strategy with a HEOR lens
Experience in Amgen products' specific therapeutic areas
Experience with direct country HTA interactions
Experience in early HTA engagement
Ability to work with customers and colleagues based in different time zones
Good presentation and communication skills
Good interpersonal and soft skills
Ability to influence without authority
Understanding of clinical development process and regulatory evidence needs
Ability to synthesize complex technical terms for non-technical audience
Strategic thinking, while focusing on tactical execution

What you can expect of us

As we work to develop treatments that take care of others, so we work to care for our teammates’ professional and personal growth and well-being.

  • Vast opportunities to learn and move up and across our global organization

  • Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act

  • Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits

Apply now

for a career that defies imagination

In our quest to serve patients above all else, Amgen is the first to imagine, and the last to doubt. Join us.

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Join Us

If you're seeking a career where you can truly make a difference in the lives of others, a career where you can work at the absolute forefront of biotechnology with the top minds in the field, you'll find it at Amgen.

Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. Our medicines have helped millions of patients in the fight against cancer, kidney disease, rheumatoid arthritis and other serious illnesses.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other but compete intensely to win. Together, we live the Amgen values as we continue advancing science to serve patients.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen requires all staff in the United States, Puerto Rico and Canada to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff.